Quality of Statins Prescription among Patients Admitted at a Tertiary Hospital in south western Nigeria: focus on cost containment

  • Onyinye Akunne University of Ibadan
  • Aduragbenro Deborah Adedapo
Keywords: Cost, prescribing pattern, DDD, Statin, Generics


Background: Cost-effective statin prescription should be encouraged especially in resource-limited setting to reduce health expenditure

Aims: The aim of the study was to assess the patterns of statin prescription and cost implication in a resource-limited setting.

Material and methods: Consecutive patients admitted into the six medical wards of the hospital were studied. Information on demographics, number and type and dose of statin prescribed was collected. Cost of statin prescription was calculated for each patient.

Results: Out of 1280 prescriptions encountered, a statin was prescribed in 59 (4.6%). The mean age was 61 years with 64% male and 36% female. A total of 62 statins were prescribed with two prescriptions containing two and three statins each. The generic prescription was low, only 18 (29%) statins were prescribed by generic name, Atorvastatin (67.8%; generic 9.7% and originator 58.1%) was the most prescribed. Average cost per month of statin was₦3 273 ($17). Potential saving from 100% generic prescription of was as much as 98%.The number of daily defined dose (DDD) per 100 patient days was 6.36 DDD. Underdosing continues to be a concern, 83% of prescribed daily doses were less than DDD.

Conclusions: A shift towards better cost-containing statin prescription is advocated. Interventions to encourage generic prescribing and improve dosing need to be implemented.


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